Jesi Lee
PhD student
UC Davis Genome Center - Metabolomics
GBSF building room 1228
451 East Health Science Drive
Davis
California
95616
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Research interest
- ·Predicting mass spectra of metabolites via ab initio and semi-empirical simulation of collision-induced dissociation
- Developing and applying in silico methods to improve compound identification rates in metabolomics
- Applying molecular dynamics to study the structure-function relationship and conformational changes of proteins and protein-ligand interactions in biochemical systems
Education
M.S. Biochemistry, San Francisco State University
B.S. Biochemistry and Molecular Cell Biology, U.C. Davis
Previous research experience
Lee, Jesi & Gokey, Trevor & Tang, Dylan& He, Zachary & Guliaev, Anton. (2018). Dimerization misalignment in human glutamate-oxaloaceatate transaminase variants is the primary factor for pyridoxal 5’-monophosphate release. PLOS ONE. 13 (9): e0203889.https://doi.org/10.1371/journal.pone.0203889.
Lee, Jesi & Gokey, Trevor & Wu, Weiming & B. Guliaev, Anton. (2018). Role of Electrostatic Interactions in Ligand Recognition by Orotidine-5’-Monophosphate Decarboxylase (ODCase). Biophysical Journal. 114. 415a-416a. 10.1016/j.bpj.2017.11.2304.
Gokey, Trevor & Lee, Jesi & B. Guliaev, Anton. (2018). Conformational Landscape of Substrate Specificity in the Fructose Transporter GLUT5 Determined via MBAR Molecular Dynamics. Biophysical Journal. 114. 135a. 10.1016/j.bpj.2017.11.763.
Baumgartner, Jackson* & Lee, Jesi* & Halavaty, Andrei & Minasov, George & Anderson, Wayne & Kuhn, Misty. (2017). Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme glucose-1-phosphate thymidylyltransferase (RfbA). Acta Crystallographica Section F Structural Biology Communications. 73. 621-628. 10.1107/S2053230X17015357. *Equally contributed.
Lee, Jesi & Ngoi, Peter & Gokey, Trevor & Chang, Xiao & Yen, Ten-Yang & Tan, Yanping & Tong, Hongyun & He, Zachary & Guliaev, Anton. (2016). Structural Framework for Pyridoxal 5'-Phosphate Binding to the Human Glutamate-Oxaloacetate Transaminase Variants. Biophysical Journal. 110. 45a. 10.1016/j.bpj.2015.11.308.