Research Topics

Cheminformatics and Compound ID

Databases & Software development

Novel Technologies

 

 

Currently Funded Projects

Date

Agilent   (PI Fiehn, O. - UC Davis)

“Metabolomic libraries and methods by mass spectrometry”

Improve metabolite identification by standardized QTOF and GC-quad MS analyses of reference compounds.

01/01/07 to 10/30/2017

NIH / NIEHS ES020819-01 (PI Hockenbery, D - U Washington/Seattle)

Biomarker discovery for mitochondrial toxicants using metabolic footprinting to examine mitochondria dysfunction at sub-chemical thresholds, centered on testing fatty acid overload and metabolite biomarker discovery as a result of BDE-47 exposure in mouse hepatocytes.

09/01/11 to 06/30/2017

P20 NIH HL113452 (PI Hazen, S. Cleveland, Fiehn, O. UC Davis; coPI)

Untargeted metabolomic analysis by GC-TOFMS and LC-QTOFMS fromblood plasma of animal models+human cohorts.

Functional Cardio-Metabolomics

06/01/12 to 05/30/2017

NSF MCB 1153491 (PI Hanson U Florida,  Fiehn, O. UC Davis; coPI et al)

Metabolite repair – Uncovering the hidden support system for metabolic networks.

04/01/12 to 03/31/2017

NSF MCB - 1139644 (PI Fiehn, O. - UC Davis)

METABOLOMICS: Integrating cheminformatic resources for investigating photoautotrophic and mixtotrophic metabolism in algae.

To implement novel metabolomic databases and tools for compound identification.

To screen 10 algal species under different environmental conditions and map metabolomic databases to algal biomass growth.

12/01/11 to 11/30/2017

NIH U24 DK097154 (PI Fiehn, O - UC Davis)

The West Coast Central Comprehensive Metabolomics Resource Core.

To provide extensive metabolomic services to biological and medical researchers on the West Coast.

09/01/12 to 08/30/2017

NIH U01 DK097430 (PI Subramaniam, S. – UCSD,     coPI  Fiehn, O)

The Metabolomics Data Center and Workbench (MDCW).

To provide a central data repository for the NIH regional Metabolomics resource cores.

09/01/12 to 08/30/2017

NIH R01 DK104351  (PI Norris, J - U Denver, CO)

Nutrigenetics & genomics of Vitamin D and Omega-3 Fatty Acids in Type 1 Diabetes.

To test food biomarkers and metabolic signatures in type 1 diabetes cohort research.

09/01/14 to 08/30/2019

NIH R01 DK89439 (PI Wojchowski, D – Maine Medical Center)

Novel regulators of stress erythropoiesis.

To provide a method for quantification of oxidized cholesteryl esters in relation to overall bound and free cholesterol levels in erythrocytes.

09/01/14 to 08/30/2019

NIH R01 DK107532 (PI Zhao, J - U Florida)

Metabolic Predictors of Diabetes in American Indians

To test metabolic signatures in type 2 diabetes cohort research.  

09/01/16 to 08/30/2020